Convergent adaptation of human lactase persistence in Africa and Europe
Tishkoff SAPapers in this archive, Reed FAPapers in this archive, Ranciaro APapers in this archive, Voight BFPapers in this archive, Babbitt CCPapers in this archive, Silverman JSPapers in this archive, Powell KPapers in this archive, Mortensen HMPapers in this archive, Hirbo JBPapers in this archive, Osman MPapers in this archive, Ibrahim MPapers in this archive, Omar SAPapers in this archive, Lema GPapers in this archive, Nyambo TBPapers in this archive, Ghori JPapers in this archive, Bumpstead SPapers in this archive, Pritchard JKPapers in this archive, Wray GAPapers in this archive, Deloukas PPapers in this archive
Abstract
A SNP in the gene encoding lactase (LCT) (C/T-13910) is associated with the ability to digest milk as adults (lactase persistence) in Europeans, but the genetic basis of lactase persistence in Africans was previously unknown. We conducted a genotype-phenotype association study in 470 Correspondence should be addressed to S.A.T. (Tishkoff@umd.edu).. 9These authors contributed equally to this work.
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