Population Genetic Data of 30 Insertion-Deletion Markers in the Polish Population
Abreu-Glowacka MPapers in this archive, Pepinski WPapers in this archive, Michalak EPapers in this archive, Konarzewska MPapers in this archive, Zak KPapers in this archive, Skawronska MPapers in this archive, Niemcunowicz-Janica APapers in this archive, Soltyszewski IPapers in this archive, Krajewski PPapers in this archive, Zaba CPapers in this archive
Abstract
(1) Background: Insertion-deletion (InDel) markers show the advantages of both short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) and are considered alternative markers in forensic genetics. (2) Methods: Allelic frequencies and corresponding forensic efficiency parameters of 30 autosomal polymorphic InDel loci included in the Investigator DIPplex kit (Qiagen) were obtained in a sample of 631 unrelated Polish individuals. Allelic frequency data were compared with those reported for selected populations (3) Results: All the loci conformed with Hardy-Weinberg equilibrium after applying a Bonferroni correction and no pair-wise significant linkage disequilibrium was detected. (4) Conclusions: DIPplex Kit differences were high among populations worldwide. The InDel markers are highly discriminating for human identification purposes in the Polish population. Keywords: Poland, population, InDels, Investigator DIPplex, forensic genetics
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