High Mitochondrial Haplotype Diversity Found in Three Pre-Hispanic Groups from Colombia
Uricoechea Patiño DPapers in this archive, Collins APapers in this archive, García OJRPapers in this archive, Santos Vecino GPapers in this archive, Cuenca JVRPapers in this archive, Bernal JEPapers in this archive, Benavides Benítez EPapers in this archive, Vergara Muñoz SPapers in this archive, Briceño Balcázar IPapers in this archive
Abstract
The analysis of mitochondrial DNA (mtDNA) hypervariable region (HVR) sequence data from ancient human remains provides valuable insights into the genetic structure and population dynamics of ancient populations. mtDNA is particularly useful in studying ancient populations, because it is maternally inherited and has a higher mutation rate compared to nuclear DNA. To determine the genetic structure of three Colombian pre-Hispanic populations and compare them with current populations, we determined the haplotypes from human bone remains by sequencing several mitochondrial DNA segments. A wide variety of mitochondrial polymorphisms were obtained from 33 samples. Our results support a high population heterogeneity among pre-Hispanic populations in Colombia.
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