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Pathogenic variation in human DNA damage repair genes was originated from the evolutionary process of modern humans
Li J, Zhao B, Qin Z, Kou SH, Chian JS, Xiao F, Lei H, Andaluz S, He J, Sinha S, Mao X, Wang SM.
Genes & diseases · doi:10.1016/j.gendis.2025.101916 · PMC12859193
Using Portuguese BRCA pathogenic variation as a model to study the impact of human admixture on human health
Andaluz S, Zhao B, Sinha S, Lagniton PNP, Costa DA, Ding X, Brito M, Wang SM.
BMC genomics · doi:10.1186/s12864-024-10311-4 · PMC11055274
Evolutionary origin of germline pathogenic variants in human DNA mismatch repair genes
Lei H, Li J, Zhao B, Kou SH, Xiao F, Chen T, Wang SM.
Human genomics · doi:10.1186/s40246-024-00573-0 · PMC10823654
Pathogenic variants in human DNA damage repair genes mostly arose in recent human history
Zhao B, Li J, Sinha S, Qin Z, Kou SH, Xiao F, Lei H, Chen T, Cao W, Ding X, Wang SM.
BMC cancer · doi:10.1186/s12885-024-12160-6 · PMC10993466
TP53 germline pathogenic variants in modern humans were likely originated during recent human history
Kou SH, Li J, Tam B, Lei H, Zhao B, Xiao F, Wang SM.
NAR cancer · doi:10.1093/narcan/zcad025 · PMC10251638