2016·Science advances
A single splice site mutation in human-specific <i>ARHGAP11B</i> causes basal progenitor amplification
Florio M, Namba T, Pääbo S, Hiller M, Huttner WB.
Read at the journaldoi:10.1126/sciadv.1601941
Abstract
Single nucleotide substitution played important role in evolutionary expansion of human neocortex. Keywords: ARHGAP11B, neocortical expansion, human evolution, basal progenitors, neurogenesis, gene duplication, neocortex, brain size, RhoGAP, human-specific gene
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