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Regulation of NAT1 activity in modern humans by a novel phosphorylation site
Fast L, Alberro ML, Rakava E, Ågren R, Riesenberg S, Huttner WB, Kelso J, Pääbo S, Zeberg H.
Science advances · doi:10.1126/sciadv.ady1666 · PMC13240207
A high-coverage Neandertal genome from the Altai Mountains reveals population structure among Neandertals
Massilani D, Peyrégne S, Iasi LNM, de Filippo C, Mafessoni F, Bossoms Mesa A, Sümer AP, Swiel Y, Popli D, Silverman S, Boyle MJ, Kozlikin MB, Shunkov MV, Der…
Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2534576123 · PMC13037865
Pleistocene chronology and history of hominins and fauna at Denisova Cave
Jacobs Z, Zavala EI, Li B, O'Gorman K, Shunkov MV, Kozlikin MB, Derevianko AP, Uliyanov VA, Goldberg P, Agadjanian AK, Vasiliev SK, Brink F, Peyrégne S, Slon…
Nature communications · doi:10.1038/s41467-025-60140-6 · PMC12095498
The activity and expression of adenylosuccinate lyase were reduced during modern human evolution, affecting brain and behavior
Ju XC, Lee SY, Ågren R, Machado LC, Xing J, Azama C, Roy MC, Endo T, Huttner W, Siepel A, Fukunaga I, Zeberg H, Pääbo S.
Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2508540122 · PMC12358879
Muscle AMP deaminase activity was lower in Neandertals than in modern humans
Macak D, Lee SY, Nyman T, Ampah-Korsah H, Strandback E, Pääbo S, Zeberg H.
Nature communications · doi:10.1038/s41467-025-61605-4 · PMC12246493
The modern human aryl hydrocarbon receptor is more active when ancestralized by genome editing
Helmbrecht N, Lackner M, Maricic T, Pääbo S.
Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2402159121 · PMC11145187
Functional dissection of two amino acid substitutions unique to the human FOXP2 protein
Bornschein U, Zeberg H, Enard W, Hevers W, Pääbo S.
Scientific reports · doi:10.1038/s41598-023-30663-3 · PMC9988825
Ancient human DNA recovered from a Palaeolithic pendant
Essel E, Zavala EI, Schulz-Kornas E, Kozlikin MB, Fewlass H, Vernot B, Shunkov MV, Derevianko AP, Douka K, Barnes I, Soulier MC, Schmidt A, Szymanski M, Tsan…
Nature · doi:10.1038/s41586-023-06035-2 · PMC10247382
Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals
Ågren R, Patil S, Zhou X, FinnGen., Sahlholm K, Pääbo S, Zeberg H.
Molecular biology and evolution · doi:10.1093/molbev/msad130 · PMC10266526
The earliest Denisovans and their cultural adaptation
Brown S, Massilani D, Kozlikin MB, Shunkov MV, Derevianko AP, Stoessel A, Jope-Street B, Meyer M, Kelso J, Pääbo S, Higham T, Douka K.
Nature ecology & evolution · doi:10.1038/s41559-021-01581-2 · PMC7612221