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Showing 1–10 of 17
Regulation of NAT1 activity in modern humans by a novel phosphorylation site
Fast L, Alberro ML, Rakava E, Ågren R, Riesenberg S, Huttner WB, Kelso J, Pääbo S, Zeberg H.
Science advances · doi:10.1126/sciadv.ady1666 · PMC13240207
A high-coverage Neandertal genome from the Altai Mountains reveals population structure among Neandertals
Massilani D, Peyrégne S, Iasi LNM, de Filippo C, Mafessoni F, Bossoms Mesa A, Sümer AP, Swiel Y, Popli D, Silverman S, Boyle MJ, Kozlikin MB, Shunkov MV, Der…
Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2534576123 · PMC13037865
The activity and expression of adenylosuccinate lyase were reduced during modern human evolution, affecting brain and behavior
Ju XC, Lee SY, Ågren R, Machado LC, Xing J, Azama C, Roy MC, Endo T, Huttner W, Siepel A, Fukunaga I, Zeberg H, Pääbo S.
Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2508540122 · PMC12358879
Muscle AMP deaminase activity was lower in Neandertals than in modern humans
Macak D, Lee SY, Nyman T, Ampah-Korsah H, Strandback E, Pääbo S, Zeberg H.
Nature communications · doi:10.1038/s41467-025-61605-4 · PMC12246493
Natural Selection of a Virus-Protective FUT2 Variant Following the Transition to Agriculture
Nordgren J, Ågren R, Hu DZ, Neijd M, Childebayeva A, Prüfer K, Hagbom M, Svensson L, Zeberg H.
Molecular biology and evolution · doi:10.1093/molbev/msaf243 · PMC12550361
Earliest modern human genomes constrain timing of Neanderthal admixture
Sümer AP, Rougier H, Villalba-Mouco V, Huang Y, Iasi LNM, Essel E, Bossoms Mesa A, Furtwaengler A, Peyrégne S, de Filippo C, Rohrlach AB, Pierini F, Mafesson…
Nature · doi:10.1038/s41586-024-08420-x · PMC11839475
Homo sapiens reached the higher latitudes of Europe by 45,000 years ago
Mylopotamitaki D, Weiss M, Fewlass H, Zavala EI, Rougier H, Sümer AP, Hajdinjak M, Smith GM, Ruebens K, Sinet-Mathiot V, Pederzani S, Essel E, Harking FS, Xi…
Nature · doi:10.1038/s41586-023-06923-7 · PMC10849966
Functional dissection of two amino acid substitutions unique to the human FOXP2 protein
Bornschein U, Zeberg H, Enard W, Hevers W, Pääbo S.
Scientific reports · doi:10.1038/s41598-023-30663-3 · PMC9988825
Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals
Ågren R, Patil S, Zhou X, FinnGen., Sahlholm K, Pääbo S, Zeberg H.
Molecular biology and evolution · doi:10.1093/molbev/msad130 · PMC10266526
A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology
Petersen J, Englmaier L, Artemov AV, Poverennaya I, Mahmoud R, Bouderlique T, Tesarova M, Deviatiiarov R, Szilvásy-Szabó A, Akkuratov EE, Pajuelo Reguera D,…
Nature communications · doi:10.1038/s41467-023-38663-7 · PMC10226981