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Showing 11–20 of 50
A substitution in the glutathione reductase lowers electron leakage and inflammation in modern humans
Coppo L, Mishra P, Siefert N, Holmgren A, Pääbo S, Zeberg H.
Science advances · doi:10.1126/sciadv.abm1148 · PMC8730399
The clinically relevant CYP2C8*3 and CYP2C9*2 haplotype is inherited from Neandertals
Haeggström S, Ingelman-Sundberg M, Pääbo S, Zeberg H.
The pharmacogenomics journal · doi:10.1038/s41397-022-00284-6 · PMC9363273
Microstratigraphic preservation of ancient faunal and hominin DNA in Pleistocene cave sediments
Massilani D, Morley MW, Mentzer SM, Aldeias V, Vernot B, Miller C, Stahlschmidt M, Kozlikin MB, Shunkov MV, Derevianko AP, Conard NJ, Wurz S, Henshilwood CS,…
Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2113666118 · PMC8740756
Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development
Mora-Bermúdez F, Kanis P, Macak D, Peters J, Naumann R, Xing L, Sarov M, Winkler S, Oegema CE, Haffner C, Wimberger P, Riesenberg S, Maricic T, Huttner WB, P…
Science advances · doi:10.1126/sciadv.abn7702 · PMC9337762
The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals
Peyrégne S, Kelso J, Peter BM, Pääbo S.
eLife · doi:10.7554/elife.75464 · PMC9273211
Genetic insights into the social organization of Neanderthals
Skov L, Peyrégne S, Popli D, Iasi LNM, Devièse T, Slon V, Zavala EI, Hajdinjak M, Sümer AP, Grote S, Bossoms Mesa A, López Herráez D, Nickel B, Nagel S, Rich…
Nature · doi:10.1038/s41586-022-05283-y · PMC9581778
Reduced purine biosynthesis in humans after their divergence from Neandertals
Stepanova V, Moczulska KE, Vacano GN, Kurochkin I, Ju X, Riesenberg S, Macak D, Maricic T, Dombrowski L, Schörnig M, Anastassiadis K, Baker O, Naumann R, Khr…
eLife · doi:10.7554/elife.58741 · PMC8133780
Pleistocene sediment DNA reveals hominin and faunal turnovers at Denisova Cave
Zavala EI, Jacobs Z, Vernot B, Shunkov MV, Kozlikin MB, Derevianko AP, Essel E, de Fillipo C, Nagel S, Richter J, Romagné F, Schmidt A, Li B, O'Gorman K, Slo…
Nature · doi:10.1038/s41586-021-03675-0 · PMC8277575
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals
Zeberg H, Pääbo S.
Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2026309118 · PMC7936282
Human Stem Cell Resources Are an Inroad to Neandertal DNA Functions
Dannemann M, He Z, Heide C, Vernot B, Sidow L, Kanton S, Weigert A, Treutlein B, Pääbo S, Kelso J, Camp JG.
Stem cell reports · doi:10.1016/j.stemcr.2020.05.018 · PMC7363959