A high-coverage Neandertal genome from Chagyrskaya Cave
Mafessoni FPapers in this archive, Grote SPapers in this archive, de Filippo CPapers in this archive, Slon VPapers in this archive, Kolobova KAPapers in this archive, Viola BPapers in this archive, Markin SVPapers in this archive, Chintalapati MPapers in this archive, Peyrégne SPapers in this archive, Skov LPapers in this archive, Skoglund PPapers in this archive, Krivoshapkin AIPapers in this archive, Derevianko APPapers in this archive, Meyer MPapers in this archive, Kelso JPapers in this archive, Peter BPapers in this archive, Prüfer KPapers in this archive, Pääbo SPapers in this archive
Abstract
We present the third high-quality genome to be determined from a Neandertal. Patterns of variation in the genome suggest that her ancestors lived in relatively isolated populations of less than 60 individuals. When we analyze this genome together with two previously sequenced Neandertal genomes, we find that genes expressed in the striatum of the brain may have changed especially much, suggesting that the striatum may have evolved unique functions in Neandertals.
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