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Neanderthal and Denisovan·2025
The activity and expression of adenylosuccinate lyase were reduced during modern human evolution, affecting brain and behavior
Ju XC, Lee SY, Ågren R, Machado LC, Xing J, Azama C, Roy MC, Endo T, Huttner W, Siepel A, Fukunaga I, Zeberg H, Pääbo S.
Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.2508540122 · PMC12358879
Neanderthal and Denisovan·2025
Muscle AMP deaminase activity was lower in Neandertals than in modern humans
Macak D, Lee SY, Nyman T, Ampah-Korsah H, Strandback E, Pääbo S, Zeberg H.
Nature communications · doi:10.1038/s41467-025-61605-4 · PMC12246493